We are interested in the ecological interactions of mosquitoes and the microorganisms that are associated with mosquito life history. The symbiotic relationship between mosquitoes and associated microbes plays essential roles in various mosquito life traits, therefore understanding of the symbiosis would facilitate to develop novel intervention strategy for the control of mosquito borne diseases.


  • Characterization and manipulation of structure and function of mosquito gut microbiome.
  • Genomics of bacterial residents in vector Anopheles and Aedes mosquitoes.
  • Ecological significance of CRISPR/CAS systems in the mosquito gut ecosystem.
  • Mosquito redox homeostasis.



  • Biol 219 Public Health Microbiology
  • Biol 311 Microbiology
  • Biol 478 Genetics of microorganisms
  • Biol 442/562 Genomics
  • Biol 446/566 Bioinformatics

The Xu lab accommodates students in various research programs, including HHMI, MARC, BRIDGES, and RISE.



Dong presented “Characterization of Type I-F of CRISPR-Cas System in Strains of Serratia spp. from the Mosquito Gut” and Dr. Xu presented “Functional Type I-F of CRISPR-CAS System is Present in the Gut Metagenome of Malaria Vector Mosquitoes” in ASM Microbe 2016.

Photo Jun 19, 11 09 05 AM

Welcome to Jiannong Xu lab